Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease

Jing Wang, Hiromi Iwasaki, Andrei Krivtsov, Phillip G Febbo, Aaron R Thorner, Patricia Ernst, Ema Anastasiadou, Jeffery L Kutok, Scott C Kogan, Sandra S Zinkel, Jill K ...

SUMMARY: Chromosomal translocations that fuse the mixed lineage leukemia (MLL) gene with multiple partners typify acute leukemias of infancy as well as therapy-related leukemias. We

CONTEXT: ...of blast cells (Figure 7D). BM sections were also notable for the presence of pseudo-Gaucher cells, which are indicative of high cell turnover and often seen in human...

The EMBO Journal 24, 368-381 (26 Jan 2005) Article

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